CTX-M-27–Producing Escherichia coli of Sequence Type 131 and Clade C1-M27, France
نویسندگان
چکیده
Author affiliations: Institut National de la Santé et de la Recherche Médicale, Paris, France (A. Birgy, P. Bidet, S. Bonacorsi); Université Paris Diderot, Paris (A. Birgy, P. Bidet, S. Bonacorsi); Hôpital Universitaire Robert-Debré, Paris (A. Birgy, P. Bidet, S. Bonacorsi); Association Clinique Thérapeutique Infantile du Val de Marne, Saint Maur des Fossés, France (C. Levy, E. Sobral, R. Cohen); Groupe de Pathologie Infectieuse Pédiatrique, Paris (C. Levy, R. Cohen); Centre Hospitalier Intercommunal de Créteil, Créteil, France (C. Levy, R. Cohen); Université Paris-Est Créteil, Créteil (C. Levy, R. Cohen)
منابع مشابه
Global Escherichia coli Sequence Type 131 Clade with blaCTX-M-27 Gene
The Escherichia coli sequence type (ST) 131 C2/H30Rx clade with the blaCTX-M-15 gene had been most responsible for the global dissemination of extended-spectrum β-lactamase (ESBL)-producing E. coli. ST131 C1/H30R with blaCTX-M-27 emerged among ESBL-producing E. coli in Japan during the late 2000s. To investigate the possible expansion of a single clade, we performed whole-genome sequencing for ...
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We examined extended-spectrum β-lactamase-producing isolates from livestock, humans, companion animals, food, and the environment during 2009-2016 in Germany for the presence of CTX-M-27 allele within Escherichia coli sequence type (ST) 131. E. coli ST131 C1-M27 was exclusively present in humans; its incidence increased from 0% in 2009 to 45% in 2016.
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The sequence type 131 (ST131)-H30 clone is responsible for a significant proportion of multidrug-resistant extraintestinal Escherichia coli infections. Recently, the C1-M27 clade of ST131-H30, associated with blaCTX-M-27, has emerged. The complete genome sequence of E. coli isolate 81009 belonging to this clone, previously used during the development of ST131-specific monoclonal antibodies, is ...
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